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Our assessment of this cohort would be that the scientific activity of MCLA-129 in 2nd line head and neck cancer appears considerably inferior to that of our guide asset petosemtamab, and only on par with other EGFR or cetuximab-based monoclonal or bispecific antibodies as monotherapy in the same setting. We feel this efficacy is inadequate to warrant further more improvement in head and neck cancer.
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We plan to start a cohort of MCLA-129 together with chemotherapy in 2L+ EGFRm NSCLC in the 1st quarter of upcoming 12 months. Moreover, we continue to be interested and are continuing investigation of cohort B analyzing MCLA-129 in clients with Fulfilled exon14 skipping NSCLC. We also continue to be considering exploring partnering MCLA-129 with other companies to adequately source the development of MCLA-129 and potential profit it could possibly have for sufferers.
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